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138 In contrast to other adipokines, plasma adiponectin levels were reduced by pro-inflammatory factors like TNF-α, IL-6, ROS, and hypoxia in animal models of obesity and IR
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A disproportionality analysis of the FDA's adverse event database found 21,281 reports of gastrointestinal toxicity among 81,752 adverse event reports for this drug class, with semaglutide carrying the strongest signal
