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To assess the incidence of suicidal ideation in patients with overweight or obesity, the study population consisted of 232,771 patients with overweight or obesity who were prescribed semaglutide (Wegovy) or non-GLP1R agonist anti-obesity medications (bupropion, naltrexone, orlistat, topiramate, phentermine, setmelanotide) 40 from 1 June 2021 through to 31 December 2022 and who had medical encounters for the diagnosis of overweight or obesity within 1 month before being prescribed anti-obesity medication, had no history of suicidal ideation before being prescribed the medication and were never prescribed other GLP1R agonist medications
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