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These include: Pancreatitis Kidney injury Allergic reactions Worsening diabetic retinopathy Medullary thyroid cancer These medications may also change how your body absorbs your other medications
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Therefore, the development of novel drug delivery systems—whether by enhancing BRB penetration or through direct ocular targeting (e.g., long-acting intravitreal formulations)—is a critical and rate-limiting step for the clinical translation of these agents